ZFIN ID: ZDB-GENE-030404-2

Gene Name:mind bomb
Gene Symbol: mib

Previous Names: chunp6889, wit(3) , fe47f05, KIAA1323(1) , white tail(3) , wu:fe47f05(1) , cg5841(1) , im:7148100(1)
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	7 figure(s) from 5 publications
Directly submitted expression data:	1 figure(s) (1 images) from Thisse et al., 2005 [eu763]
	1 figure(s) (1 images) from Thisse et al., 2004 [IMAGE:7148100]
Wild Type Stages, Structures:	Zygote:1-cell (0.00h-0.75h) to Hatching:Pec-fin (60.00h-72.00h)
	brain, hindbrain ... (all 6)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   43 genotypes
Allele(s):   hi904Tg, m132, m178, ta52b, tfi101 ... (all 7)

Phenotype: (current status)

Data:	32 figures from 22 publications
Observed in:	apoptosis, artery, auditory receptor cell fate specification, axon, axon guidance ... (all 67)

Knockdown reagents: MO1-mib (1) ,   MO2-mib (1) ,   MO3-mib (1) ,   MO4-mib (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	protein autoubiquitination (more)
Cellular Component	cytoplasm (more)
Molecular Function	protein homodimerization activity (more)

All GO Terms (44)

Protein Families, Domains and Sites:

InterPro:IPR000433 (1) InterPro:IPR001841 (1) InterPro:IPR002110 (1) InterPro:IPR010606 (1) InterPro:IPR020683 (1)

PROSITE:PS00518 (1) PROSITE:PS01357 (1) PROSITE:PS50088 (1) PROSITE:PS50089 (1) PROSITE:PS50135 (1) PROSITE:PS50297 (1) PROSITE:PS51416 (1)

Pfam:PF00023 (1) Pfam:PF00569 (1) Pfam:PF06701 (1)

EC:6.3.2.- (1)

Gene Product Description

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

mib Contained in	[BAC] DKEY-2P18 (1)    (order this) [FOSMID] CH1073-221A23 (1)    (order this)
mib Encodes	[EST] eu763 (1) , fe47f05 , IMAGE:7148100 (1)    (order this) [cDNA] MGC:193576 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_173286 (1)	3293 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX842700 (1)	198258 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:B3DGQ0 (1)	1041 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:124112 (1)
All Sequence Information (16)

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OTHER  mib  GENE / MARKER PAGES:

Entrez Gene:352910 (1)

VEGA:OTTDARG00000019100 (1)

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MAPPING INFORMATION:

LG:  2    Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	FC
Zebrafish	mib	2
Human	MIB1	18 (q11.2)	OMIM:608677 Entrez Gene:57534
Mouse	Mib1	18 (syntenic)	MGI:2443157 Entrez Gene:225164
Fruit fly	CG5841	3L	FLYBASE:FBgn0036558
Orthology Details

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CITATIONS   (132)