Gene
cox8a
- ID
- ZDB-GENE-030131-9136
- Name
- cytochrome c oxidase subunit 8A
- Symbol
- cox8a Nomenclature History
- Previous Names
-
- coxXVIII (1)
- fb01d11
- hm:zehn2228
- wu:fb01d11
- zehn2228
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in oxidative phosphorylation. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Predicted to be active in mitochondrion. Is expressed in brain; gill; heart; liver; and skeletal muscle. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COX8A (cytochrome c oxidase subunit 8A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Little et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 15 | Alliance | ?Mitochondrial complex IV deficiency, nuclear type 15 | 619059 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome c oxidase, subunit 8 | Cytochrome c oxidase, subunit 8 superfamily |
|---|---|---|---|
|
UniProtKB:E9QFA6
|
76 |
Interactions and Pathways
No data available
Plasmids
No data available