ZFIN is now using GRCz12tu for Genomic Data
Gene
bcan
- ID
- ZDB-GENE-030131-6045
- Name
- brevican
- Symbol
- bcan Nomenclature History
- Previous Names
-
- fi32a12
- wu:fi32a12
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable carbohydrate binding activity and hyaluronic acid binding activity. Predicted to be involved in central nervous system development and skeletal system development. Predicted to act upstream of or within cell adhesion. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space; perineuronal net; and synapse. Is expressed in VeLD and forebrain. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human BCAN (brevican).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Staudt et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
| Conserved_site | IPR018378 | C-type lectin, conserved site |
| Domain | IPR000436 | Sushi/SCR/CCP domain |
| Domain | IPR000538 | Link domain |
| Domain | IPR000742 | EGF-like domain |
| Domain | IPR001304 | C-type lectin-like |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013106 | Immunoglobulin V-set domain |
| Family | IPR050691 | Hyaluronan-binding Proteoglycan |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR016186 | C-type lectin-like/link domain superfamily |
| Homologous_superfamily | IPR016187 | C-type lectin fold |
| Homologous_superfamily | IPR035976 | Sushi/SCR/CCP superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | C-type lectin, conserved site | C-type lectin fold | C-type lectin-like | C-type lectin-like/link domain superfamily | EGF-like domain | Hyaluronan-binding Proteoglycan | Immunoglobulin domain subtype | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | Immunoglobulin V-set domain | Link domain | Sushi/SCR/CCP domain | Sushi/SCR/CCP superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A4JYN2 | InterPro | 1295 | |||||||||||||||
| UniProtKB:A0AB32T2B4 | InterPro | 1303 | |||||||||||||||
| UniProtKB:A0AB32T3J9 | InterPro | 1301 | |||||||||||||||
| UniProtKB:A0AB32T475 | InterPro | 1301 | |||||||||||||||
| UniProtKB:A0AB32T4L8 | InterPro | 1297 | |||||||||||||||
| UniProtKB:A0AB32T608 | InterPro | 1300 | |||||||||||||||
| UniProtKB:A0AB32T7X2 | InterPro | 1302 | |||||||||||||||
| UniProtKB:A0A8M1NCN0 | InterPro | 1295 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers