ZFIN ID: ZDB-GENE-030131-6045
Gene Name: brevican
Gene Symbol: bcan    Nomenclature History

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Previous Names: fi32a12, wu:fi32a12

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have hyaluronic acid binding activity. Predicted to be involved in central nervous system development and skeletal system development. Predicted to localize to extracellular matrix. Is expressed in VeLD and forebrain. Orthologous to human BCAN (brevican).
Genome Resources: Alliance (1),  Gene:334113 (1),  Ensembl(GRCz11):ENSDARG00000099412 (1)
GENE EXPRESSION
All Expression Data: Fig. 2 from Staudt et al., 2015
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la019694Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1944 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10253 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36168 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH bcan HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH bcan VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell adhesion (more)
    Cellular Component extracellular matrix (more)
    Molecular Function hyaluronic acid binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA bcan-201 (1)    Ensembl 5529
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    AB1-bcan monoclonal Mouse IHC 1
    CONSTRUCTS WITH SEQUENCES FROM bcan No data available
    MARKER RELATIONSHIPS
    bcan Contained in: [BAC] DKEY-235H8 (1) (order this)
    bcan Encodes: [EST] fi32a12
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001083813 (1) 5607 nt
    Genomic GenBank:CR848047 (1) 166830 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IXT8 (1) 1295 aa
    Sequence Information (all 13)
    ORTHOLOGY for bcan ( Chr: 16 )
    CITATIONS (25)