ZFIN ID: ZDB-GENE-030131-574

Gene Name:intraflagellar transport 88 homolog
Gene Symbol: ift88

Previous Names: xx:zah8127, ovl, fb37b11, wu:fb37b11, ttc10(1) , intraflagellar transport protein 88(1) , polaris(1) , oval
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	9 figure(s) from 6 publications
Wild Type Stages, Structures:	Zygote:1-cell (0.00h-0.75h) to Adult (90d-730d, breeding adult)
	brain, eye ... (all 12)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   7 genotypes
Allele(s):   tz288, unspecified_ift88

Phenotype: (current status)

Data:	15 figures from 6 publications
Observed in:	blue sensitive photoreceptor cell, cell migration, cilium, cilium assembly, eye ... (all 23)

Knockdown reagents: MO1-ift88 (1) ,   MO2-ift88 (1) ,   MO3-ift88 (1) ,   MO4-ift88 (1) ,   MO5-ift88 (1) ,   MO6-ift88 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	determination of left/right symmetry (more)
Cellular Component	axoneme (more)
Molecular Function	binding

All GO Terms (13)

Protein Families, Domains and Sites:

InterPro:IPR001440 (1) InterPro:IPR006597 (1) InterPro:IPR011990 (1) InterPro:IPR013026 (1) InterPro:IPR019734 (1)

PROSITE:PS50005 (1) PROSITE:PS50293 (1)

Pfam:PF00515 (1)

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ANTIBODIES:

Ab1-ift88 (2)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

ift88 Contained in	[BAC] DKEY-51D17 (1)    (order this)
ift88 Encodes	[EST] fb37b11 , zah8127 [cDNA] MGC:193654 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001001725 (1)	2897 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR392366 (1)	125898 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:B0UYB0 (1)	824 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:2900 (1)
All Sequence Information (21)

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OTHER  ift88  GENE / MARKER PAGES:

Entrez Gene:321855 (1)

VEGA:OTTDARG00000020500 (1)

Ensembl(Zv8):ENSDARG00000027234 (1)

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MAPPING INFORMATION:

LG:  13 ,  9    Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	NT	CL
Zebrafish	ift88	13 ,  9
Human	IFT88	13 (q12.1)	OMIM:600595 Entrez Gene:8100
Mouse	Ift88	14 (21.00 cM)	MGI:98715 Entrez Gene:21821
Orthology Details

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CITATIONS   (39)