ZFIN ID: ZDB-GENE-030131-574
Gene Name: intraflagellar transport 88 homolog
Gene Symbol: ift88
Sequence Ontology ID : SO:0000704

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Previous Names: ovl, fb37b11, intraflagellar transport protein 88 (1), oval, polaris (1), ttc10 (1), wu:fb37b11, xx:zah8127

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(Including Attributions)
Location: Chr: 9 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 21 figures from 13 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  brain, eye, eye photoreceptor cell cilium, eye photoreceptor cell photoreceptor connecting cilium (all 20) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ift88_unspecified Unspecified Unknown Unknown
sa7628 Point Mutation Unknown Nonsynonymous ENU
sa8799 Point Mutation Unknown Premature Stop ENU
sa18944 Point Mutation Unknown Premature Stop ENU
sa27381 Point Mutation Unknown Premature Stop ENU
sa41401 Point Mutation Unknown Splice Site ENU
tz288 Point Mutation Exon 11 Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: CRISPR1-ift88 (1), CRISPR2-ift88 (1), CRISPR3-ift88 (1), MO1-ift88 (1), MO2-ift88 (1) (all 10) expand
    PHENOTYPE
    Data: 39 figures from 24 publications
    Observed in: anterior macula stereocilium bundle, atrioventricular canal endocardium, blue sensitive photoreceptor cell, brain (all 67) expand
    DISEASE ASSOCIATED WITH ift88 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of left/right symmetry (more)
    Cellular Component axoneme (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011990 (1)
  • InterPro:IPR013026 (1)
  • InterPro:IPR019734 (1)
  • PROSITE:PS50005 (1)
  • PROSITE:PS50293 (1)
  • Pfam:PF13174 (1)
  • Pfam:PF13181 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ift88-001 (1) 2941
    ift88-002 (1) 602
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-ift88 (1), Ab2-ift88 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ift88 No data available
    MARKER RELATIONSHIPS
    ift88Contained in: [BAC] DKEY-51D17 (1) (order this)
    ift88Encodes: [EST] fb37b11, zah8127
    [cDNA] MGC:193654 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001725 (1) 2897bp
    Genomic GenBank:CR392366 (1) 125898bp
    Select Tool
    Polypeptide UniProtKB:F1QVN7 (1) 855aa
    Sequence Clusters UniGene:2900 (1)
    Sequence Information (all 40)
    OTHER ift88 GENE PAGES
  • Alliance (1)
  • Gene:321855 (1)
  • VEGA:OTTDARG00000020500 (1)
  • Ensembl(GRCz10):ENSDARG00000027234 (1)
  • ORTHOLOGY for ift88 (Chr: 9)
    CITATIONS (79)