Gene

camsap2a

ID

ZDB-GENE-030131-3016

Name

calmodulin regulated spectrin-associated protein family, member 2a

Symbol

camsap2a Nomenclature History

Previous Names

camsap1l1
camsap2
si:dkey-39e8.1
wu:fc16g04
wu:fc23h08

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to enable microtubule minus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization and negative regulation of microtubule depolymerization. Predicted to act upstream of or within neuron projection development. Predicted to be located in cytoplasm and microtubule. Predicted to colocalize with microtubule minus-end. Is expressed in external yolk syncytial layer; internal yolk syncytial layer; and yolk syncytial layer. Orthologous to human CAMSAP2 (calmodulin regulated spectrin associated protein family member 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With camsap2a Human Ortholog

No data available

Associated With camsap2a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR031372	CAMSAP, spectrin and Ca2+/calmodulin-binding region
Domain	IPR001715	Calponin homology domain
Domain	IPR014797	CKK domain
Domain	IPR022613	Calmodulin-regulated spectrin-associated protein-like, Calponin-homology domain
Family	IPR032940	Calmodulin-regulated spectrin-associated protein
Homologous_superfamily	IPR011033	PRC-barrel-like superfamily
Homologous_superfamily	IPR036872	CH domain superfamily
Homologous_superfamily	IPR038209	CKK domain superfamily

Domain Details Per Protein

Protein	Length	Calmodulin-regulated spectrin-associated protein	Calmodulin-regulated spectrin-associated protein-like, Calponin-homology domain	Calponin homology domain	CAMSAP, spectrin and Ca2+/calmodulin-binding region	CH domain superfamily	CKK domain	CKK domain superfamily	PRC-barrel-like superfamily
UniProtKB:A0A8M2BHT9 InterPro	1404
UniProtKB:A0A8M3B5I3 InterPro	1423
UniProtKB:A0A8M2BHT6 InterPro	1415
UniProtKB:Q1LUF1 InterPro	1407
UniProtKB:A0A8M3AN06 InterPro	1412