Research
General Information
ZIRC
ZFIN: Gene: lamc1
ZFIN ID: ZDB-GENE-021226-3

Gene Name:laminin, gamma 1
Gene Symbol: lamc1
Previous Names: shp, sly, sleepy, shortstop
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 8 figure(s) from 3 publications
Directly submitted expression data: 6 figure(s) (20 images) from Thisse et al., 2004 [MGC:85930]
Wild Type Stages, Structures: Blastula:1k-cell (3.00h-3.33h) to Hatching:Long-pec (48.00h-60.00h)
  adaxial cell, epidermis ... (all 20)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   35 genotypes
Allele(s):   cz61, hi1193Tg, hi2557Tg, hi3890Tg, hi4131Tg ... (all 26)
Phenotype: (current status)
  Data: 44 figures from 12 publications
  Observed in: actin filament organization, apical part of cell, basal part of cell, basement membrane, brain ... (all 44)
Knockdown reagents: MO1-lamc1 (1) ,   MO2-lamc1 (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process detection of light stimulus involved in visual perception (more)
Cellular Component basement membrane (more)
All GO Terms (9)

Protein Families, Domains and Sites:
  • InterPro:IPR000034 (1)
  • InterPro:IPR002049 (1)
  • InterPro:IPR008211 (1)
  • InterPro:IPR018031 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01248 (1)
  • PROSITE:PS50027 (1)
  • PROSITE:PS51115 (1)
  • PROSITE:PS51117 (1)
  • Pfam:PF00052 (1)
  • Pfam:PF00053 (1)
  • Pfam:PF00055 (1)
  • Loading Transcript Data...

    Gene Product Description


    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    lamc1 Contained in [BAC] CH211-194I4 (1)    (order this) , DKEY-161L11 (1)    (order this)
    lamc1 Encodes [cDNA] MGC:85930 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173277 (1) 6055 bp
    Genomic GenBank:BX681417 (1) 233760 bp
    Polypeptide UniProtKB:Q1LVF0 (1) 1593 aa
    Sequence Clusters UniGene:132970 (1)
    All Sequence Information (12)

    OTHER  lamc1  GENE / MARKER PAGES:

  • Entrez Gene:286832 (1)
  • VEGA:OTTDARG00000017017 (1)
  • Ensembl(Zv8):ENSDARG00000036279 (1)

  • MAPPING INFORMATION:
      LG:  2    Details

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA IX
    Zebrafish lamc1  2
    Human LAMC1  1 (q31)
  • OMIM:150290
  • Entrez Gene:3915
  • Mouse Lamc1  1 (81.10 cM)
  • MGI:99914
  • Entrez Gene:226519
  • Orthology Details

    CITATIONS   (46)