Research
General Information
ZIRC
ZFIN: Gene: lamb1
ZFIN ID: ZDB-GENE-021226-1

Gene Name:laminin, beta 1
Gene Symbol: lamb1
Previous Names: sb:cb95, gup, fc20b05, grumpy, cb95(1) , wu:fc20b05
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 8 figure(s) from 3 publications
Directly submitted expression data: 6 figure(s) (18 images) from Thisse et al., 2001 [cb95]
Wild Type Stages, Structures: Blastula:1k-cell (3.00h-3.33h) to Hatching:Long-pec (48.00h-60.00h)
  apical ectodermal ridge pectoral fin bud, axis ... (all 25)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   25 genotypes
Allele(s):   hi1113bTg, hi1297Tg, hi3181Tg, m135, m189 ... (all 17)
Phenotype: (current status)
  Data: 33 figures from 11 publications
  Observed in: basement membrane, brain, cell, cranial nerve II, detection of light stimulus involved in visual perception ... (all 37)
Knockdown reagent: MO1-lamb1 (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process detection of light stimulus involved in visual perception (more)
Cellular Component proteinaceous extracellular matrix
All GO Terms (5)

Protein Families, Domains and Sites:
  • InterPro:IPR002049 (1)
  • InterPro:IPR008211 (1)
  • InterPro:IPR008979 (1)
  • InterPro:IPR013015 (1)
  • InterPro:IPR013032 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01248 (1)
  • PROSITE:PS50027 (1)
  • PROSITE:PS51116 (1)
  • PROSITE:PS51117 (1)
  • Pfam:PF00053 (1)
  • Pfam:PF00055 (1)

  • SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    lamb1 Encodes [EST] cb95    (order this) , fc20b05 (1)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_173275 (1) 5358 bp
    Polypeptide UniProtKB:Q8JHV7 (1) 1785 aa
    Sequence Clusters UniGene:76526 (1)
    All Sequence Information (13)

    OTHER  lamb1  GENE / MARKER PAGES:

  • Entrez Gene:286830 (1)
  • Ensembl(Zv8):ENSDARG00000026491 (1)

  • MAPPING INFORMATION:
      LG:  25  Details

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish lamb1  25
    Human LAMB1  7 (q22)
  • OMIM:150240
  • Entrez Gene:3912
  • Orthology Details

    CITATIONS   (38)