Gene
arl13b
- ID
- ZDB-GENE-021217-3
- Name
- ADP-ribosylation factor-like 13b
- Symbol
- arl13b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity. Involved in cilium assembly and photoreceptor cell outer segment organization. Localizes to cilium. Human ortholog(s) of this gene implicated in Joubert syndrome 8. Is expressed in Kupffer's vesicle; nervous system; otic vesicle; and pronephros. Orthologous to human ARL13B (ADP ribosylation factor like GTPase 13B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 25 figures from 14 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Joubert syndrome 8 | Alliance | Joubert syndrome 8 | 612291 |
Human Disease | Fish | Conditions | Citations |
---|---|---|---|
Joubert syndrome 8 | arl13bhi459Tg/hi459Tg | standard conditions | Zhu et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Ciliary function-associated GTPase | P-loop containing nucleoside triphosphate hydrolase | Small GTPase superfamily, ARF/SAR type |
---|---|---|---|---|
UniProtKB:Q8JHI3
|
407 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
arl13b-201
(1)
|
Havana | 2808 nt | |
mRNA |
arl13b-202
(1)
|
Havana | 2153 nt | |
ncRNA |
arl13b-003
(1)
|
Havana | 520 nt |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-arl13b | polyclonal | Rabbit |
|
Covance
|
11 |
Plasmids
No data available