ZFIN ID: ZDB-GENE-020919-4

Gene Name:ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Gene Symbol: st8sia2

Previous Names: Stx(1) , id:ibd5161, siat8, cb394(1)
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	18 figure(s) from 6 publications
Directly submitted expression data:	6 figure(s) (14 images) from Thisse et al., 2001 [cb394]
	4 figure(s) (5 images) from Kudoh et al., 2001 [ibd5161]
Wild Type Stages, Structures:	Blastula:128-cell (2.25h-2.50h) to Adult (90d-730d, breeding adult)
	basal plate midbrain region, brain ... (all 46)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Phenotype: (current status)

Data:	1 figure from Marx et al., 2007
Observed in:	axon guidance, diencephalic white matter

Knockdown reagents: MO1-st8sia2 (1) ,   MO2-st8sia2 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Molecular Function	sialyltransferase activity (more)
Biological Process	protein amino acid glycosylation
Cellular Component	Golgi apparatus (more)

All GO Terms (8)

Protein Families, Domains and Sites:

InterPro:IPR001675 (1) InterPro:IPR012163 (1)

Pfam:PF00777 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

st8sia2 Contained in	[BAC] CH211-196L7 (1)    (order this)
st8sia2 Encodes	[EST] cb394 (1)    (order this) , ibd5161    (order this) [cDNA] MGC:55237 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_153662 (1)	2326 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX649578 (1)	211922 bp	- Select Tool - MegaBLAST
Polypeptide	UniProtKB:Q50J31 (1)	383 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:31925 (1)
All Sequence Information (17)

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OTHER  st8sia2  GENE / MARKER PAGES:

Entrez Gene:555134 (1)

VEGA:OTTDARG00000013664 (1)

Ensembl(Zv8):ENSDARG00000018788 (1)

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MAPPING INFORMATION:

LG:  18  Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	st8sia2	18
Human	ST8SIA2	15 (q26)	OMIM:602546 Entrez Gene:8128
Mouse	St8sia2	Unknown	MGI:106020 Entrez Gene:20450
Orthology Details

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CITATIONS   (19)