ZFIN is now using GRCz12tu for Genomic Data
Gene
rfc3
- ID
- ZDB-GENE-020809-3
- Name
- replication factor C (activator 1) 3
- Symbol
- rfc3 Nomenclature History
- Previous Names
-
- cb275 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable ATP hydrolysis activity and DNA binding activity. Predicted to contribute to DNA clamp loader activity. Predicted to be involved in DNA repair and DNA-templated DNA replication. Predicted to act upstream of or within DNA replication. Predicted to be part of DNA replication factor C complex. Predicted to be active in nucleus. Is expressed in alar plate midbrain region; head; immature eye; optic tectum; and pectoral fin musculature. Orthologous to human RFC3 (replication factor C subunit 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb275 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Family | IPR050238 | DNA Replication and Repair Clamp Loader Complex |
| Homologous_superfamily | IPR008921 | DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Additional Resources | Length | AAA+ ATPase domain | DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal | DNA Replication and Repair Clamp Loader Complex | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|
| UniProtKB:Q8AW06 | InterPro | 356 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers