ZFIN ID: ZDB-GENE-020419-32

Gene Name:histone deacetylase 1
Gene Symbol: hdac1

Previous Names: chunp6919, wu:fi06f03(1) , wu:fb19h11(1) , colgate, mp:zf637-2-001987, zgc:65818(1) , hdac-1(1) , zgc:101582, col
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	13 figure(s) from 5 publications
Directly submitted expression data:	7 figure(s) (9 images) from Thisse et al., 2008 [MGC:101582]
	1 figure(s) (1 images) from Thisse et al., 2004 [IMAGE:6904025]
Wild Type Stages, Structures:	Zygote:1-cell (0.00h-0.75h) to Larval:Day 5 (120.00h-144.00h, 3.9mm, 6 teeth)
	brain, eye ... (all 11)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   22 genotypes
Allele(s):   b382, hi1618Tg, hi2628Tg, rw399, s436 ... (all 8)

Phenotype: (current status)

Data:	24 figures from 7 publications
Observed in:	brain, cartilage, cell, CNS neuron (sensu Vertebrata), common lymphocyte progenitor ... (all 43)

Knockdown reagent: MO1-hdac1

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	Wnt receptor signaling pathway (more)
Molecular Function	histone deacetylase activity (more)

All GO Terms (17)

Protein Families, Domains and Sites:

InterPro:IPR000286 (1) InterPro:IPR003084 (1)

Pfam:PF00850 (1)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

hdac1 Encodes

[EST] fb19h11 (1) , fi06f03 (1) , IMAGE:6904025 (1)    (order this) , zf637-2-001987 [STS] chunp6919 [cDNA] MGC:65818    (order this) , MGC:101582 (1)    (order this) , MGC:193070 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_173236 (1)	2213 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Polypeptide	UniProtKB:Q5RKQ4 (1)	480 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:31752 (1)
All Sequence Information (20)

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OTHER  hdac1  GENE / MARKER PAGES:

Entrez Gene:192302 (1)

Ensembl(Zv8):ENSDARG00000015427 (1)

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MAPPING INFORMATION:

LG:  19  Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	NT	CL
Zebrafish	hdac1	19
Human	HDAC1	1 (p34)	OMIM:601241 Entrez Gene:3065
Mouse	Hdac1	Unknown	MGI:108086 Entrez Gene:433759
Orthology Details

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CITATIONS   (41)