Gene

vim

ID
ZDB-GENE-011212-3
Name
vimentin
Symbol
vim Nomenclature History
Previous Names
  • cb28 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Involved in wound healing. Predicted to localize to intermediate filament. Human ortholog(s) of this gene implicated in Behcet's disease; atherosclerosis; autoimmune hypersensitivity disease (multiple); cataract 30; and rheumatoid arthritis. Is expressed in several structures, including axis; integument; midbrain neural keel; nervous system; and neural tube. Orthologous to human VIM (vimentin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
26 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from LeBert et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vim Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cataract 30 Alliance Cataract 30, pulverulent 116300
Associated With vim Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018039 Intermediate filament protein, conserved site
Domain IPR006821 Intermediate filament head, DNA-binding domain
Domain IPR039008 Intermediate filament, rod domain
Family IPR050405 Intermediate filament structural protein
Domain Details Per Protein
Protein Length Intermediate filament head, DNA-binding domain Intermediate filament protein, conserved site Intermediate filament, rod domain Intermediate filament structural protein
UniProtKB:A0A8M9PXB1 417
UniProtKB:Q9YHX5 455
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA vim-201 (1) Ensembl 1,861 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-vim monoclonal IgG1 Mouse
  • IHC
  • WB
Sigma-Aldrich
Millipore
Dako North America, Inc.
Abcam plc
Novus Biologicals, LLC
Vector Laboratories
13
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations