ZFIN ID: ZDB-GENE-011119-1

Gene Name:glypican 4
Gene Symbol: gpc4

Previous Names: gpc6, gpc4/6, knypek(1) , chunp6920, fe05f10, wu:fe05f10(1) , kny(1) , fc47a08, wu:fc47a08(1)
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	2 figure(s) from 2 publications
Wild Type Stages, Structures:	Gastrula:75%-epiboly (8.00h-9.00h) to Segmentation:10-13 somites (14.00h-16.00h)
	axial chorda mesoderm, tail bud
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   28 genotypes
Allele(s):   b404, b639, fr6, hi1688Tg, hi1934Tg ... (all 12)

Phenotype: (current status)

Data:	16 figures from 10 publications
Observed in:	adaxial cell, axis, cell migration involved in gastrulation, cell morphogenesis, convergent extension involved in axis elongation ... (all 19)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	cell migration involved in gastrulation (more)
Cellular Component	anchored to membrane (more)
Molecular Function	protein binding (more)

All GO Terms (15)

Protein Families, Domains and Sites:

InterPro:IPR001863 (1)

Pfam:PF01153 (1)

Gene Product Description

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

gpc4 Contained in	[BAC] CH211-191O15 (1)    (order this) , DKEY-57B1 (1)    (order this)
gpc4 Encodes	[EST] fc47a08 , fe05f10 (1) [STS] chunp6920 [cDNA] MGC:194854 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131860 (1)	1822 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX530080 (1)	165220 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:B3DJ94 (1)	557 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:78935 (1)
All Sequence Information (13)

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OTHER  gpc4  GENE / MARKER PAGES:

Entrez Gene:118437 (1)

VEGA:OTTDARG00000027978 (1)

Ensembl(Zv8):ENSDARG00000015472 (1)

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MAPPING INFORMATION:

LG:  14  Details

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	CL
Zebrafish	gpc4	14
Human	GPC4	X (q26.1)	OMIM:300168 Entrez Gene:2239
Mouse	Gpc4	Unknown	MGI:104902 Entrez Gene:14735
Orthology Details

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CITATIONS   (50)