Research
General Information
ZIRC
ZFIN: Gene: eomesa
ZFIN ID: ZDB-GENE-001228-1

Gene Name:eomesodermin homolog a
Gene Symbol: eomesa
Previous Names: tbr2(1) , eom(1) , tbr2a(1) , eomes, eomes1(1)
Nomenclature History


GENE EXPRESSION:(current status)
All expression data: 26 figure(s) from 13 publications
Directly submitted expression data: 7 figure(s) (12 images) from Thisse et al., 2005 [eu170]
Wild Type Stages, Structures: Zygote:1-cell (0.00h-0.75h) to Adult (90d-730d, breeding adult)
  blastodisc, diencephalon ... (all 20)
Curated microarray expression: GEO  (1)

MUTANTS AND TARGETED KNOCKDOWNS:
Mutant line(s):   3 genotypes
Allele(s):   fh105, unrec_eomesa
Phenotype: (current status)
Knockdown reagents: MO1-eomesa (1) ,   MO2-eomesa (1) ,   MO3-eomesa (1) ,   MO4-eomesa (1)

GENE PRODUCTS:

Gene Ontology
Ontology GO Term
Biological Process endoderm formation (more)
Cellular Component cytoplasm (more)
Molecular Function DNA binding (more)
All GO Terms (11)

Protein Families, Domains and Sites:
  • InterPro:IPR001699 (1)
  • InterPro:IPR008967 (1)
  • InterPro:IPR018186 (1)
  • PROSITE:PS01264 (1)
  • PROSITE:PS01283 (1)
  • PROSITE:PS50252 (1)
  • Pfam:PF00907 (1)
  • Gene Product Description


    CONSTRUCTS WITH SEQUENCE FROM eomesa:
    Tg(-5eomesa:DsRed)

    SEGMENT (CLONE AND PROBE) RELATIONSHIPS:
    eomesa Encodes [EST] eu170 (1)
    [cDNA] MGC:85959 (1)    (order this) , MGC:173895 (1)    (order this)

    SEQUENCE INFORMATION:
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131679 (1) 2572 bp
    Polypeptide UniProtKB:Q98TU2 (1) 661 aa
    Sequence Clusters UniGene:83042 (1)
    All Sequence Information (13)

    OTHER  eomesa  GENE / MARKER PAGES:

  • Entrez Gene:64603 (1)
  • Ensembl(Zv8):ENSDARG00000006640 (1)

  • MAPPING INFORMATION:
      LG:  19  Details   View Map: Merged  Individual Panels

    ORTHOLOGY:
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish eomesa  19
    Human EOMES  3 (p24.1)
  • OMIM:604615
  • Entrez Gene:8320
  • Mouse Eomes  9 (67.00 cM)
  • MGI:1201683
  • Entrez Gene:13813
  • Orthology Details

    CITATIONS   (34)