ZFIN Lab: Pachnis Lab

ZFIN ID: ZDB-LAB-170314-1

Pachnis Lab

PI/Director:	Pachnis, V.
Contact Person:	Heanue, Tiffany A.
Email:	tiffany.heanue@crick.ac.uk
URL:
Address:	Development and Homeostasis of the Nervous System Lab The Francis Crick Institute 1 Midland Road London NW1 1AT
Country:	United Kingdom
Phone:	+44 203 796 1556
Fax:
Line Designation:	fci

GENOMIC FEATURES ORIGINATING FROM THIS LAB

Show all 2 genomic features

STATEMENT OF RESEARCH INTERESTS

LAB MEMBERS

Heanue, Tiffany A. Post-Doc

ZEBRAFISH PUBLICATIONS OF LAB MEMBERS

McCallum, S., Obata, Y., Fourli, E., Boeing, S., Peddie, C.J., Xu, Q., Horswell, S., Kelsh, R., Collinson, L., Wilkinson, D., Pin, C., Pachnis, V., Heanue, T.A. (2020) Enteric glia as a source of neural progenitors in adult zebrafish. eLIFE. 9:

Heanue, T.A., Boesmans, W., Bell, D.M., Kawakami, K., Vanden Berghe, P., Pachnis, V. (2016) A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity. PLoS Genetics. 12:e1006439

Heanue, T.A., Shepherd, I.T., Burns, A.J. (2016) Enteric Nervous System Development in Avian and Zebrafish Models. Developmental Biology. 417(2):129-38

Kaucka, M., Ivashkin, E., Gyllborg, D., Zikmund, T., Tesarova, M., Kaiser, J., Xie, M., Petersen, J., Pachnis, V., Nicolis, S.K., Yu, T., Sharpe, P., Arenas, E., Brismar, H., Blom, H., Clevers, H., Suter, U., Chagin, A.S., Fried, K., Hellander, A., Adameyko, I. (2016) Analysis of neural crest-derived clones reveals novel aspects of facial development. Science advances. 2:e1600060

Jiang, Q., Arnold, S., Heanue, T., Kilambi, K.P., Doan, B., Kapoor, A., Ling, A.Y., Sosa, M.X., Guy, M., Jiang, Q., Burzynski, G., West, K., Bessling, S., Griseri, P., Amiel, J., Fernandez, R.M., Verheij, J.B., Hofstra, R.M., Borrego, S., Lyonnet, S., Ceccherini, I., Gray, J.J., Pachnis, V., McCallion, A.S., Chakravarti, A. (2015) Functional Loss of Semaphorin 3C and/or Semaphorin 3D and Their Epistatic Interaction with Ret Are Critical to Hirschsprung Disease Liability. American journal of human genetics. 96:581-596

Knight, R.D., Mebus, K., d'Angelo, A., Yokoya, K., Heanue, T., and Roehl, H. (2011) Ret signalling integrates a craniofacial muscle module during development. Development (Cambridge, England). 138(10):2015-2024

Heanue, T.A., and Pachnis, V. (2008) Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species. Mechanisms of Development. 125(8):687-699

Marcos-Gutiérrez, C.V., Wilson, S.W., Holder, N., and Pachnis, V. (1997) The zebrafish homologue of the ret receptor and its pattern of expression during embryogenesis. Oncogene. 14(8):879-889