ZFIN Person: Pachnis, V.

ZFIN ID: ZDB-PERS-970327-8

Pachnis, V.

Email:	vassils.pachnis@crick.ac.uk
URL:
Affiliation:	Pachnis Lab
Address:	Scientific Program Leader Development and Homeostasis of the Nervous System Lab The Francis Crick Institute 1 Midland Road London NW1 1AT
Country:
Phone:	+44 203 796 1556
Fax:
ORCID ID:	0000-0001-9733-7686

BIOGRAPHY AND RESEARCH INTERESTS

PUBLICATIONS

McCallum, S., Obata, Y., Fourli, E., Boeing, S., Peddie, C.J., Xu, Q., Horswell, S., Kelsh, R., Collinson, L., Wilkinson, D., Pin, C., Pachnis, V., Heanue, T.A. (2020) Enteric glia as a source of neural progenitors in adult zebrafish. eLIFE. 9:

Heanue, T.A., Boesmans, W., Bell, D.M., Kawakami, K., Vanden Berghe, P., Pachnis, V. (2016) A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity. PLoS Genetics. 12:e1006439

Kaucka, M., Ivashkin, E., Gyllborg, D., Zikmund, T., Tesarova, M., Kaiser, J., Xie, M., Petersen, J., Pachnis, V., Nicolis, S.K., Yu, T., Sharpe, P., Arenas, E., Brismar, H., Blom, H., Clevers, H., Suter, U., Chagin, A.S., Fried, K., Hellander, A., Adameyko, I. (2016) Analysis of neural crest-derived clones reveals novel aspects of facial development. Science advances. 2:e1600060

Jiang, Q., Arnold, S., Heanue, T., Kilambi, K.P., Doan, B., Kapoor, A., Ling, A.Y., Sosa, M.X., Guy, M., Jiang, Q., Burzynski, G., West, K., Bessling, S., Griseri, P., Amiel, J., Fernandez, R.M., Verheij, J.B., Hofstra, R.M., Borrego, S., Lyonnet, S., Ceccherini, I., Gray, J.J., Pachnis, V., McCallion, A.S., Chakravarti, A. (2015) Functional Loss of Semaphorin 3C and/or Semaphorin 3D and Their Epistatic Interaction with Ret Are Critical to Hirschsprung Disease Liability. American journal of human genetics. 96:581-596

Heanue, T.A., and Pachnis, V. (2008) Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species. Mechanisms of Development. 125(8):687-699

Marcos-Gutiérrez, C.V., Wilson, S.W., Holder, N., and Pachnis, V. (1997) The zebrafish homologue of the ret receptor and its pattern of expression during embryogenesis. Oncogene. 14(8):879-889

NON-ZEBRAFISH PUBLICATIONS