Gene
ncam1a
- ID
- ZDB-GENE-990415-31
- Name
- neural cell adhesion molecule 1a
- Symbol
- ncam1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Acts upstream of or within posterior commissure morphogenesis. Predicted to be located in plasma membrane. Is expressed in several structures, including anterior neural keel; myotome; nervous system; optic vesicle; and pectoral fin. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; bipolar disorder; drug dependence; middle cerebral artery infarction; and nicotine dependence. Orthologous to human NCAM1 (neural cell adhesion molecule 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 27 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d828 (14 images)
- eu303 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Langhauser et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR003961 | Fibronectin type III |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Family | IPR009138 | Neural cell adhesion |
| Family | IPR051170 | Neural and epithelial cell adhesion domain-containing protein |
| Family | IPR051275 | Cellular adhesion and signaling domain-containing protein |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036116 | Fibronectin type III superfamily |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cellular adhesion and signaling domain-containing protein | Fibronectin type III | Fibronectin type III superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Neural and epithelial cell adhesion domain-containing protein | Neural cell adhesion |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2B821 | InterPro | 989 | |||||||||||
| UniProtKB:A0A8M2B824 | InterPro | 978 | |||||||||||
| UniProtKB:A0A8M3B4M6 | InterPro | 994 | |||||||||||
| UniProtKB:A0A8M2B827 | InterPro | 749 | |||||||||||
| UniProtKB:A0A8M3ATS9 | InterPro | 1010 | |||||||||||
| UniProtKB:A0A8M3ALE2 | InterPro | 1000 | |||||||||||
| UniProtKB:A0A8M2B8D1 | InterPro | 988 | |||||||||||
| UniProtKB:A0A8M3AWT0 | InterPro | 652 | |||||||||||
| UniProtKB:A0A8M6YUF3 | InterPro | 727 | |||||||||||
| UniProtKB:A0A8M2B851 | InterPro | 717 | |||||||||||
| UniProtKB:B3DH85 | InterPro | 837 | |||||||||||
| UniProtKB:A0A8M6Z3L2 | InterPro | 995 | |||||||||||
| UniProtKB:A0A8M3AM36 | InterPro | 869 | |||||||||||
| UniProtKB:A0A8M2B837 | InterPro | 1005 | |||||||||||
| UniProtKB:A0A8M6Z2Y4 | InterPro | 854 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ncam1a-201
(1)
|
Ensembl | 2,921 nt | ||
| mRNA |
ncam1a-202
(1)
|
Ensembl | 878 nt | ||
| mRNA |
ncam1a-206
(1)
|
Ensembl | 2,810 nt | ||
| mRNA |
ncam1a-207
(1)
|
Ensembl | 2,840 nt | ||
| ncRNA |
ncam1a-002
(1)
|
Ensembl | 903 nt | ||
| ncRNA |
ncam1a-004
(1)
|
Ensembl | 665 nt | ||
| ncRNA |
ncam1a-005
(1)
|
Ensembl | 528 nt |
Interactions and Pathways
No data available
Plasmids
No data available