Gene
wnt11
- ID
- ZDB-GENE-980526-249
- Name
- wingless-type MMTV integration site family, member 11
- Symbol
- wnt11 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within embryonic morphogenesis; neuromast development; and pharyngeal system development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; fin; mesoderm; nervous system; and pharyngeal arch. Human ortholog(s) of this gene implicated in oral squamous cell carcinoma. Orthologous to human WNT11 (Wnt family member 11).
- Genome Resources
- Note
-
From Postlethwait et al. (2019) "analysis of phylogenies and conserved syntenies from sequenced genomes clarifies the evolutionary history and nomenclature of the Wnt11 gene family to better connect teleost models of human disease to human biology."
- Comparative Information
-
- All Expression Data
- 48 figures from 23 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:76804 (19 images)
- eu556 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Wnt | Wnt, C-terminal domain | Wnt protein, conserved site |
|---|---|---|---|---|
|
UniProtKB:Q9I9I2
|
352 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
wnt11r-201
(1)
|
Ensembl | 2,171 nt |
Interactions and Pathways
No data available
Plasmids
No data available