Gene

slc16a1a

ID

ZDB-GENE-110408-16

Name

solute carrier family 16 member 1a

Symbol

slc16a1a Nomenclature History

Previous Names

si:ch211-105j21.7

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to enable lactate:proton symporter activity. Predicted to be involved in plasma membrane lactate transport. Predicted to act upstream of or within monocarboxylic acid transport and transmembrane transport. Predicted to be located in apical plasma membrane. Predicted to be active in basolateral plasma membrane. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 7. Orthologous to human SLC16A1 (solute carrier family 16 member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With slc16a1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
familial hyperinsulinemic hypoglycemia 7	Alliance	Hyperinsulinemic hypoglycemia, familial, 7	610021
		Erythrocyte lactate transporter defect	245340
		Monocarboxylate transporter 1 deficiency	616095

Associated With slc16a1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR020846	Major facilitator superfamily domain
Family	IPR004743	Monocarboxylate transporter
Family	IPR011701	Major facilitator superfamily
Family	IPR050327	Proton-linked Monocarboxylate Transporter
Homologous_superfamily	IPR036259	MFS transporter superfamily

Domain Details Per Protein

Protein	Length	Major facilitator superfamily	Major facilitator superfamily domain	MFS transporter superfamily	Monocarboxylate transporter	Proton-linked Monocarboxylate Transporter
UniProtKB:H1ABV8 InterPro	461
UniProtKB:E7F7B3 InterPro	461

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	slc16a1a-201 (1) Ensembl	Ensembl	2,429 nt	Select Tool ZFIN BLAST
mRNA	slc16a1a-202 (1) Ensembl	Ensembl	2,439 nt	Select Tool ZFIN BLAST
mRNA	slc16a1a-203 (1) Ensembl	Ensembl	1,386 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations