Gene
kdm2ab
- ID
- ZDB-GENE-101007-5
- Name
- lysine (K)-specific demethylase 2Ab
- Symbol
- kdm2ab Nomenclature History
- Previous Names
-
- jhdm1A-a (1)
- unm_sa1479
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable histone demethylase activity and transcription coregulator activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human KDM2A (lysine demethylase 2A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019786 | Zinc finger, PHD-type, conserved site |
| Domain | IPR001810 | F-box domain |
| Domain | IPR001965 | Zinc finger, PHD-type |
| Domain | IPR002857 | Zinc finger, CXXC-type |
| Domain | IPR003347 | JmjC domain |
| Domain | IPR019787 | Zinc finger, PHD-finger |
| Domain | IPR041070 | Jumonji, helical domain |
| Family | IPR050690 | JHDM1 Histone Demethylase |
| Homologous_superfamily | IPR011011 | Zinc finger, FYVE/PHD-type |
| Homologous_superfamily | IPR013083 | Zinc finger, RING/FYVE/PHD-type |
| Homologous_superfamily | IPR032675 | Leucine-rich repeat domain superfamily |
| Repeat | IPR006553 | Leucine-rich repeat, cysteine-containing subtype |
Domain Details Per Protein
| Protein | Length | F-box domain | JHDM1 Histone Demethylase | JmjC domain | Jumonji, helical domain | Leucine-rich repeat, cysteine-containing subtype | Leucine-rich repeat domain superfamily | Zinc finger, CXXC-type | Zinc finger, FYVE/PHD-type | Zinc finger, PHD-finger | Zinc finger, PHD-type | Zinc finger, PHD-type, conserved site | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M1PZC6
|
1263 | ||||||||||||
|
UniProtKB:E7F0J6
|
1253 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kdm2ab-201
(1)
|
Ensembl | 7,078 nt | ||
| mRNA |
kdm2ab-202
(1)
|
Ensembl | 3,816 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance