Gene

pum1

ID
ZDB-GENE-030131-2074
Name
pumilio RNA-binding family member 1
Symbol
pum1 Nomenclature History
Previous Names
  • fb96a03
  • si:ch211-285e16.1
  • wu:fb96a03
  • wu:fb96a08
  • zgc:63671
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have mRNA 3'-UTR binding activity. Predicted to be involved in production of miRNAs involved in gene silencing by miRNA and regulation of mRNA stability. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in cerebellar ataxia type 47. Orthologous to human PUM1 (pumilio RNA binding family member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pum1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
cerebellar ataxia type 47 Alliance Spinocerebellar ataxia 47 617931
Neurodevelopmental disorder with motor abnormalities, seizures, and facial dysmorphism 620719
Associated With pum1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR033133 Pumilio homology domain
Domain IPR033712 Pumilio, RNA binding domain
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR016024 Armadillo-type fold
Repeat IPR001313 Pumilio RNA-binding repeat
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold Pumilio homology domain Pumilio, RNA binding domain Pumilio RNA-binding repeat
UniProtKB:A0A0R4IWL6 1152
UniProtKB:S6B5C2 1152
UniProtKB:Q7SXY5 540
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-pum1 polyclonal Rabbit
  • IHC
  • WB
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations