Gene
itga8
- ID
- ZDB-GENE-080220-48
- Name
- integrin, alpha 8
- Symbol
- itga8 Nomenclature History
- Previous Names
-
- zgc:172265
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Involved in cilium assembly and embryonic viscerocranium morphogenesis. Predicted to localize to integrin complex. Human ortholog(s) of this gene implicated in end stage renal failure; ovarian cancer; renal agenesis; and schizophrenia. Is expressed in hair cell; head; inner ear; neuromast hair cell; and pharyngeal arch. Orthologous to human ITGA8 (integrin subunit alpha 8).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
renal agenesis | Alliance | Renal hypodysplasia/aplasia 1 | 191830 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein | Length |
---|---|
UniProtKB:A0A8M9PK29
|
1059 |
Interactions and Pathways
No data available
Plasmids
No data available