Gene
tbc1d4
- ID
- ZDB-GENE-030131-9881
- Name
- TBC1 domain family, member 4
- Symbol
- tbc1d4 Nomenclature History
- Previous Names
-
- cb53 (1)
- sb:cb53
- si:ch211-222g23.4
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity and Rab GTPase binding activity. Predicted to be involved in activation of GTPase activity and intracellular protein transport. Human ortholog(s) of this gene implicated in acanthosis nigricans. Is expressed in myotome; pancreatic bud; pronephric duct; and segmental plate. Orthologous to human TBC1D4 (TBC1 domain family member 4).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 4 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb53 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
{Diabetes mellitus, noninsulin-dependent, 5} | 616087 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Domain of unknown function DUF3350 | PH-like domain superfamily | PTB/PI domain | Rab-GAP-TBC domain | Rab-GAP-TBC domain superfamily |
---|---|---|---|---|---|---|
UniProtKB:A0A8M3B5R8
|
1195 | |||||
UniProtKB:A0A8M2BF73
|
1247 | |||||
UniProtKB:A0A8M2BF88
|
1246 | |||||
UniProtKB:A0A8M9QG34
|
514 | |||||
UniProtKB:A0A8M2BF77
|
1196 | |||||
UniProtKB:A0A8M1RM25
|
1246 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
tbc1d4-201
(1)
|
Havana | 4019 nt | |
mRNA |
tbc1d4-202
(1)
|
Havana | 756 nt |
Interactions and Pathways
No data available
Plasmids
No data available