Gene

qdpra

ID
ZDB-GENE-070705-197
Name
quinoid dihydropteridine reductase a
Symbol
qdpra Nomenclature History
Previous Names
  • dhpra (1)
  • si:ch211-89f22.2
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to have 6,7-dihydropteridine reductase activity; NADH binding activity; and NADPH binding activity. Predicted to be involved in L-phenylalanine catabolic process and tetrahydrobiopterin biosynthetic process. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in phenylketonuria. Orthologous to human QDPR (quinoid dihydropteridine reductase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Breuer et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Breuer et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With qdpra Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
BH4-deficient hyperphenylalaninemia C Alliance Hyperphenylalaninemia, BH4-deficient, C 261630
Associated With qdpra Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase, conserved site Short-chain dehydrogenase/reductase SDR
UniProtKB:A7YT77 237
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA qdpra-201 (1) Havana 4656 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations