Gene
git2a
- ID
- ZDB-GENE-060526-267
- Name
- G protein-coupled receptor kinase interacting ArfGAP 2a
- Symbol
- git2a Nomenclature History
- Previous Names
-
- git2
- si:dkey-234h16.4
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity and metal ion binding activity. Involved in cell migration involved in gastrulation and regulation of cell morphogenesis. Orthologous to human GIT2 (GIT ArfGAP 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Yu et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Yu et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001164 | Arf GTPase activating protein |
| Domain | IPR013724 | GIT, Spa2 homology (SHD) domain |
| Domain | IPR022018 | ARF GTPase-activating protein GIT1, C-terminal |
| Domain | IPR032352 | Arf GTPase-activating protein GIT1/2, coiled-coil domain |
| Family | IPR047161 | ARF GTPase-activating protein Git-like |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Homologous_superfamily | IPR037278 | ARFGAP/RecO-like zinc finger |
| Homologous_superfamily | IPR038508 | ArfGAP domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf GTPase activating protein | Arf GTPase-activating protein GIT1/2, coiled-coil domain | ARF GTPase-activating protein GIT1, C-terminal | ARF GTPase-activating protein Git-like | GIT, Spa2 homology (SHD) domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q912
|
432 | |||||||||
|
UniProtKB:A0A8M2BCD7
|
804 | |||||||||
|
UniProtKB:A0A8M2BCH9
|
802 | |||||||||
|
UniProtKB:A0A8M3ASB4
|
752 | |||||||||
|
UniProtKB:A2BG45
|
750 | |||||||||
|
UniProtKB:A0A8M9QEB8
|
746 | |||||||||
|
UniProtKB:A0A8M3B2D0
|
710 |
Interactions and Pathways
No data available
Plasmids
No data available