ZFIN is now using GRCz12tu for Genomic Data
Gene
actl6b
- ID
- ZDB-GENE-050522-191
- Name
- actin like 6B
- Symbol
- actl6b Nomenclature History
- Previous Names
-
- zgc:110167
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in nervous system development. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 76 and intellectual disability. Orthologous to human ACTL6B (actin like 6B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110167 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| developmental and epileptic encephalopathy 76 | Alliance | Developmental and epileptic encephalopathy 76 | 618468 |
| Intellectual developmental disorder with severe speech and ambulation defects | 618470 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Actin, conserved site | Actin family | ATPase, nucleotide binding domain |
|---|---|---|---|---|---|
| UniProtKB:F8W3Z2 | InterPro | 426 | |||
| UniProtKB:Q503T4 | InterPro | 376 | |||
| UniProtKB:A0ACD6B6U2 | InterPro | 426 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
actl6b-201
(1)
|
Ensembl | 1,131 nt | ||
| mRNA |
actl6b-202
(1)
|
Ensembl | 1,592 nt | ||
| mRNA | si:ch1073-228j22.3-001 (1) | 1,281 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers