Gene

sema3c

ID

ZDB-GENE-050513-5

Name

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C

Symbol

sema3c Nomenclature History

Previous Names

si:dkey-105o6.1 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Exhibits neuropilin binding activity. Involved in enteric nervous system development. Predicted to localize to extracellular space and integral component of plasma membrane. Is expressed in caudal tuberculum and otic vesicle. Orthologous to human SEMA3C (semaphorin 3C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Jiang et al., 2015
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sema3c Human Ortholog

No data available

Associated With sema3c Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001627	Sema domain
Domain	IPR003599	Immunoglobulin subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR016201	PSI domain
Family	IPR027231	Semaphorin
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily
Homologous_superfamily	IPR036352	Sema domain superfamily

Domain Details Per Protein

Protein	Length	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype	PSI domain	Sema domain	Sema domain superfamily	Semaphorin	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A0A8M6Z658 InterPro	757

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	sema3c-201 (1) Ensembl	Havana	2141 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations