Gene

prl2

ID

ZDB-GENE-041210-160

Name

prolactin 2

Symbol

prl2 Nomenclature History

Previous Names

PRL-L (1)
si:dkey-261e22.3 (1)

Type

protein_coding_gene

Location

Chr: 4 Mapping Details/Browsers

Description

Predicted to have hormone activity. Predicted to be involved in positive regulation of receptor signaling pathway via JAK-STAT and response to nutrient levels. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in carotid artery disease. Is expressed in brain; eye; gill; muscle; and pleuroperitoneal region. Orthologous to human PRL (prolactin).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With prl2 Human Ortholog

No data available

Associated With prl2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018116	Somatotropin hormone, conserved site
Family	IPR001400	Somatotropin/prolactin
Homologous_superfamily	IPR009079	Four-helical cytokine-like, core