Gene

prl2

ID
ZDB-GENE-041210-160
Name
prolactin 2
Symbol
prl2 Nomenclature History
Previous Names
  • PRL-L (1)
  • si:dkey-261e22.3 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have hormone activity. Predicted to be involved in positive regulation of receptor signaling pathway via JAK-STAT and response to nutrient levels. Predicted to localize to extracellular space. Is expressed in brain; eye; gill; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human PRL (prolactin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prl2 Human Ortholog
No data available
Associated With prl2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018116 Somatotropin hormone, conserved site
Family IPR001400 Somatotropin/prolactin
Homologous_superfamily IPR009079 Four-helical cytokine-like, core
Domain Details Per Protein
Protein Length Four-helical cytokine-like, core Somatotropin hormone, conserved site Somatotropin/prolactin
UniProtKB:C6ZDB8 226
UniProtKB:F1QZ85 237
UniProtKB:C6G3Y2 226
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-prl2 polyclonal Rabbit
  • IHC
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations