Gene
shroom4
- ID
- ZDB-GENE-041111-246
- Name
- shroom family member 4
- Symbol
- shroom4 Nomenclature History
- Previous Names
-
- im:7145757
- wu:fe05h01
- zgc:194172
- zgc:194173
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in several cellular components, including adherens junction; apical junction complex; and apical plasma membrane. Human ortholog(s) of this gene implicated in Stocco Dos Santos type X-linked intellectual disability. Orthologous to human SHROOM4 (shroom family member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7145757 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Kolvenbach et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Apx/Shrm Domain 2 | PDZ domain | PDZ superfamily | Shroom family |
|---|---|---|---|---|---|
|
UniProtKB:A0A8N7TES2
|
1508 | ||||
|
UniProtKB:F1Q6C1
|
1634 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
shroom4-201
(1)
|
Ensembl | 6,362 nt | ||
| mRNA |
shroom4-202
(1)
|
Ensembl | 541 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-shroom4 | polyclonal | Rabbit |
|
2 |
Plasmids
No data available