Gene

shroom4

ID
ZDB-GENE-041111-246
Name
shroom family member 4
Symbol
shroom4 Nomenclature History
Previous Names
  • im:7145757
  • wu:fe05h01
  • zgc:194172
  • zgc:194173
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in actin filament organization. Predicted to localize to several cellular components, including adherens junction; apical junction complex; and apical plasma membrane. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Orthologous to human SHROOM4 (shroom family member 4).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With shroom4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Stocco dos Santos X-linked mental retardation syndrome 300434
Associated With shroom4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001478 PDZ domain
Domain IPR014799 Apx/Shrm Domain 2
Family IPR027685 Shroom family
Family IPR027687 Shroom4
Homologous_superfamily IPR036034 PDZ superfamily
Domain Details Per Protein
Protein Length Apx/Shrm Domain 2 PDZ domain PDZ superfamily Shroom4 Shroom family
UniProtKB:B3DGK9 99
UniProtKB:F1Q6C1 1634
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations