Gene
pomcb
- ID
- ZDB-GENE-041014-294
- Name
- proopiomelanocortin b
- Symbol
- pomcb Nomenclature History
- Previous Names
-
- pomc-like (1)
- si:ch211-203k16.2
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have neuropeptide hormone activity. Involved in regulation of hematopoietic stem cell differentiation. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in familial Mediterranean fever; obesity; and osteoarthritis. Is expressed in brain and preoptic area. Orthologous to human POMC (proopiomelanocortin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Shi et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Opiodes neuropeptide | Pro-opiomelanocortin | Pro-opiomelanocortin/corticotropin, ACTH, central region |
|---|---|---|---|---|
|
UniProtKB:A0A8M1NCD8
|
215 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-pomc | monoclonal | IgG1 | Mouse |
|
LifeSpan BioSciences, Inc.
|
2 |
Plasmids
No data available