Gene
pomcb
- ID
- ZDB-GENE-041014-294
- Name
- proopiomelanocortin b
- Symbol
- pomcb Nomenclature History
- Previous Names
-
- pomc-like (1)
- si:ch211-203k16.2
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have neuropeptide hormone activity. Involved in regulation of hematopoietic stem cell differentiation. Predicted to localize to extracellular region. Is expressed in brain and preoptic area. Human ortholog(s) of this gene implicated in familial Mediterranean fever; obesity; and osteoarthritis. Orthologous to human POMC (proopiomelanocortin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Shi et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Opiodes neuropeptide | Pro-opiomelanocortin | Pro-opiomelanocortin/corticotropin, ACTH, central region |
|---|---|---|---|---|
|
UniProtKB:Q5SPP4
|
215 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-pomc | monoclonal | IgG1 | Mouse |
|
LifeSpan BioSciences, Inc.
|
2 |
Plasmids
No data available