ZFIN ID: ZDB-GENE-041014-294
Gene Name: proopiomelanocortin b
Gene Symbol: pomcb
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: pomc-like (1), si:ch211-203k16.2

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(Including Attributions)
Location: Chr: 20 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Day 4 (96.0h-120.0h)
  preoptic area, whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23794 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-pomcb (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pomcb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    obesity {Obesity, early-onset, susceptibility to} 601665
    Obesity, adrenal insufficiency, and red hair due to POMC deficiency 609734
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process neuropeptide signaling pathway (more)
    Cellular Component extracellular region (more)
    Molecular Function hormone activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001941 (1)
  • InterPro:IPR013531 (1)
  • InterPro:IPR013532 (1)
  • Pfam:PF00976 (1)
  • Pfam:PF08035 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pomcb-001 (1) 648
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pomcb No data available
    MARKER RELATIONSHIPS
    pomcbContained in: [BAC] CH211-203K16 (1) (order this), DKEYP-70E6 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001083051 (1) 648bp
    Genomic GenBank:BX324115 (1) 202547bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q5SPP4 (1) 215aa
    Sequence Clusters UniGene:135611 (1)
    Sequence Information (all 11)
    OTHER pomcb GENE PAGES
  • Alliance (1)
  • Gene:100034412 (1)
  • VEGA:OTTDARG00000006374 (1)
  • Ensembl(GRCz10):ENSDARG00000069307 (1)
  • ORTHOLOGY for pomcb (Chr: 20)
    CITATIONS (27)