Gene
spout1
- ID
- ZDB-GENE-040912-53
- Name
- SPOUT domain containing methyltransferase 1
- Symbol
- spout1 Nomenclature History
- Previous Names
-
- cb90 (1)
- sb:cb90
- zgc:101748
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to enable miRNA binding activity. Predicted to be involved in maintenance of centrosome location and miRNA processing. Predicted to be located in cytoplasm. Predicted to be active in kinetochore; mitotic spindle; and spindle pole centrosome. Is expressed in several structures, including blood; central nervous system; neural tube; optic vesicle; and tail bud. Orthologous to human SPOUT1 (SPOUT domain containing methyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7160913 (1 image)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with poor growth, seizures, and brain abnormalities | 621154 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Alpha/beta knot methyltransferases | Nucleic acid-binding, OB-fold | Putative RNA methyltransferase C9orf114-like | tRNA (guanine-N1-)-methyltransferase, N-terminal |
|---|---|---|---|---|---|---|
| UniProtKB:Q66ID3 | InterPro | 381 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spout1-201
(1)
|
Ensembl | 1,396 nt | ||
| mRNA |
spout1-203
(1)
|
Ensembl | 722 nt | ||
| mRNA |
spout1-204
(1)
|
Ensembl | 918 nt | ||
| ncRNA |
zgc:101748-004
(1)
|
Ensembl | 810 nt |
Interactions and Pathways
No data available
Plasmids
No data available