Gene
nme5
- ID
- ZDB-GENE-040718-221
- Name
- NME/NM23 family member 5
- Symbol
- nme5 Nomenclature History
- Previous Names
-
- NM23-Z5 (1)
- zgc:92812
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have nucleoside diphosphate kinase activity. Predicted to be involved in negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway. Is expressed in Kupffer's vesicle; forerunner cell group; male organism; nervous system; and pleuroperitoneal region. Orthologous to human NME5 (NME/NM23 family member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92812 (19 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Cho et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ciliary dyskinesia, primary, 48, without situs inversus | 620032 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| primary ciliary dyskinesia | AB + MO1-nme5 | standard conditions | Cho et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dpy-30 motif | Nucleoside diphosphate kinase | Nucleoside diphosphate kinase-like domain | Nucleoside diphosphate kinase-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q6DGQ8
|
217 |
Interactions and Pathways
No data available
Plasmids
No data available