Gene
nrp1b
- ID
- ZDB-GENE-040611-1
- Name
- neuropilin 1b
- Symbol
- nrp1b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to have growth factor binding activity; metal ion binding activity; and transmembrane signaling receptor activity. Involved in several processes, including axon guidance; regulation of vascular endothelial growth factor receptor signaling pathway; and vasculature development. Predicted to localize to integral component of membrane. Is expressed in cranial neural crest cell; mid cerebral vein; retinal ganglion cell layer; somite; and trunk vasculature. Orthologous to human NRP1 (neuropilin 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000421 | Coagulation factor 5/8 C-terminal domain |
| Domain | IPR000859 | CUB domain |
| Domain | IPR000998 | MAM domain |
| Domain | IPR022579 | Neuropilin, C-terminal |
| Family | IPR014648 | Neuropilin |
| Homologous_superfamily | IPR008979 | Galactose-binding-like domain superfamily |
| Homologous_superfamily | IPR013320 | Concanavalin A-like lectin/glucanase domain superfamily |
| Homologous_superfamily | IPR035914 | Spermadhesin, CUB domain superfamily |
Domain Details Per Protein
| Protein | Length | Coagulation factor 5/8 C-terminal domain | Concanavalin A-like lectin/glucanase domain superfamily | CUB domain | Galactose-binding-like domain superfamily | MAM domain | Neuropilin | Neuropilin, C-terminal | Spermadhesin, CUB domain superfamily |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6T870
|
959 |
Interactions and Pathways
No data available
Plasmids
No data available