Gene
mhc1zba
- ID
- ZDB-GENE-040426-2149
- Name
- major histocompatibility complex class I ZBA
- Symbol
- mhc1zba Nomenclature History
- Previous Names
-
- zgc:64115 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to be involved in immune response. Predicted to localize to external side of plasma membrane and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including acute porphyria (multiple); arthritis (multiple); bone marrow cancer (multiple); hemochromatosis (multiple); and liver disease (multiple). Is expressed in gill; intestine; kidney; liver; and spleen. Orthologous to several human genes including AZGP1 (alpha-2-glycoprotein 1, zinc-binding); HFE (homeostatic iron regulator); and HLA-E (major histocompatibility complex, class I, E).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR003006 | Immunoglobulin/major histocompatibility complex, conserved site |
Domain | IPR001039 | MHC class I alpha chain, alpha1 alpha2 domains |
Domain | IPR003597 | Immunoglobulin C1-set |
Domain | IPR007110 | Immunoglobulin-like domain |
Domain | IPR011161 | MHC class I-like antigen recognition-like |
Homologous_superfamily | IPR011162 | MHC classes I/II-like antigen recognition protein |
Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
Homologous_superfamily | IPR037055 | MHC class I-like antigen recognition-like superfamily |
Domain Details Per Protein
Protein | Length | Immunoglobulin C1-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin/major histocompatibility complex, conserved site | MHC classes I/II-like antigen recognition protein | MHC class I alpha chain, alpha1 alpha2 domains | MHC class I-like antigen recognition-like | MHC class I-like antigen recognition-like superfamily |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A8E7F4
|
398 | |||||||||
UniProtKB:A0A0N4STQ1
|
308 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
mhc1zba-201
(1)
|
Havana | 2323 nt |
Interactions and Pathways
No data available
Plasmids
No data available