Gene

rlbp1b

ID

ZDB-GENE-040426-1870

Name

retinaldehyde binding protein 1b

Symbol

rlbp1b Nomenclature History

Previous Names

cralbpa (1)
rlbp1
rlbp1a (1)
zgc:77766

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to have phosphatidylinositol bisphosphate binding activity. Involved in optokinetic behavior. Human ortholog(s) of this gene implicated in Bothnia retinal dystrophy; Newfoundland cone-rod dystrophy; fundus albipunctatus; night blindness; and retinitis pigmentosa. Is expressed in optic vesicle; otic vesicle; pericardial region; pronephric duct; and sensory system. Orthologous to human RLBP1 (retinaldehyde binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

20 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77766 (16 images)
IMAGE:6897952 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rlbp1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Bothnia retinal dystrophy	607475
		Fundus albipunctatus	136880
		Newfoundland rod-cone dystrophy	607476
		Retinitis punctata albescens	136880

Associated With rlbp1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001251	CRAL-TRIO lipid binding domain
Domain	IPR011074	CRAL/TRIO, N-terminal domain
Homologous_superfamily	IPR036273	CRAL/TRIO, N-terminal domain superfamily
Homologous_superfamily	IPR036865	CRAL-TRIO lipid binding domain superfamily

Domain Details Per Protein

Protein	Length	CRAL-TRIO lipid binding domain	CRAL-TRIO lipid binding domain superfamily	CRAL/TRIO, N-terminal domain	CRAL/TRIO, N-terminal domain superfamily
UniProtKB:Q6P027 InterPro	307

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rlbp1b-201 (1) Ensembl	Ensembl	1653 nt	Select Tool ZFIN BLAST
mRNA	rlbp1b-202 (1) Ensembl	Havana	1520 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-rlbp	polyclonal	rlbp1a rlbp1b		Rabbit	IHC WB		3

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations