Gene

hao2

ID
ZDB-GENE-040426-1239
Name
hydroxyacid oxidase 2 (long chain)
Symbol
hao2 Nomenclature History
Previous Names
  • zgc:63690
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have L-lactate dehydrogenase activity and carnosine synthase activity. Predicted to be involved in carnosine biosynthetic process and lactate oxidation. Is expressed in lens; liver; pronephric duct; solid lens vesicle; and yolk syncytial layer. Orthologous to human HAO2 (hydroxyacid oxidase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hao2 Human Ortholog
No data available
Associated With hao2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site
Domain IPR000262 FMN-dependent dehydrogenase
Domain IPR037396 FMN hydroxy acid dehydrogenase domain
Family IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent
Homologous_superfamily IPR013785 Aldolase-type TIM barrel
Domain Details Per Protein
Protein Length Aldolase-type TIM barrel Alpha-hydroxy acid dehydrogenase, FMN-dependent FMN-dependent alpha-hydroxy acid dehydrogenase, active site FMN-dependent dehydrogenase FMN hydroxy acid dehydrogenase domain
UniProtKB:Q7SXX8 357
UniProtKB:F1QCD8 357
UniProtKB:A0A8M2BF11 378
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hao2-201 (1) Ensembl 1,795 nt
mRNA hao2-202 (1) Ensembl 602 nt
mRNA hao2-203 (1) Ensembl 773 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations