Gene

arhgap4a

ID

ZDB-GENE-040426-1229

Name

Rho GTPase activating protein 4a

Symbol

arhgap4a Nomenclature History

Previous Names

zgc:63672

Type

protein_coding_gene

Location

Chr: 23 Mapping Details/Browsers

Description

Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of cell migration; nervous system development; and regulation of synapse assembly. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human ARHGAP4 (Rho GTPase activating protein 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arhgap4a Human Ortholog

No data available

Associated With arhgap4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000198	Rho GTPase-activating protein domain
Domain	IPR001060	FCH domain
Domain	IPR001452	SH3 domain
Domain	IPR031160	F-BAR domain
Domain	IPR035678	srGAP4, SH3 domain
Family	IPR051627	SLIT-ROBO Rho GTPase-activating
Homologous_superfamily	IPR008936	Rho GTPase activation protein
Homologous_superfamily	IPR027267	AH/BAR domain superfamily
Homologous_superfamily	IPR036028	SH3-like domain superfamily