Gene

mao

ID
ZDB-GENE-040329-3
Name
monoamine oxidase
Symbol
mao Nomenclature History
Previous Names
  • wu:fb68b05
  • wu:fo76d11
  • wu:fq38g06
  • Z-MAO (1)
  • zgc:85761
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Exhibits primary amine oxidase activity. Involved in cellular biogenic amine catabolic process. Predicted to localize to integral component of membrane and mitochondrial outer membrane. Human ortholog(s) of this gene implicated in Brunner Syndrome; alcohol use disorder; autism spectrum disorder; neurodegenerative disease (multiple); and panic disorder. Is expressed in brain; digestive system; gill; heart; and neurons. Orthologous to several human genes including MAOB (monoamine oxidase B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from Baronio et al., 2021
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mao Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Brunner Syndrome Alliance Brunner syndrome 300615
Brunner Syndrome Alliance {Antisocial behavior} 300615
Associated With mao Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002937 Amine oxidase
Family IPR001613 Flavin amine oxidase
Homologous_superfamily IPR036188 FAD/NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length Amine oxidase FAD/NAD(P)-binding domain superfamily Flavin amine oxidase
UniProtKB:Q6NSN2 522
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations