Gene
gfi1ab
- ID
- ZDB-GENE-040116-8
- Name
- growth factor independent 1A transcription repressor b
- Symbol
- gfi1ab Nomenclature History
- Previous Names
-
- gfi1.2
- gfi1
- gfi1b
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in peripheral nervous system development. Predicted to localize to nuclear chromatin. Is expressed in anterior lateral mesoderm; nervous system; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in acute myeloid leukemia and severe congenital neutropenia. Orthologous to human GFI1 (growth factor independent 1 transcriptional repressor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 36 figures from 22 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Yu et al., 2020
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
---|---|---|---|
UniProtKB:Q7SZV1
|
396 |
Type | Name | Annotation Method | Length (nt) | Analysis |
---|---|---|---|---|
mRNA |
gfi1ab-201
(1)
|
Havana | 1228 nt |
Interactions and Pathways
No data available
Plasmids
No data available