ZFIN is now using GRCz12tu for Genomic Data
Gene
dock2
- ID
- ZDB-GENE-031125-1
- Name
- dedicator of cytokinesis 2
- Symbol
- dock2 Nomenclature History
- Previous Names
-
- cb1005 (1)
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in small GTPase-mediated signal transduction. Predicted to be located in cytoplasm and membrane. Is expressed in macrophage. Human ortholog(s) of this gene implicated in immunodeficiency 40. Orthologous to human DOCK2 (dedicator of cytokinesis 2).
- Genome Resources
-
- Alliance (1)
- Gene:100330200 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1005 (3 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 40 | Alliance | Immunodeficiency 40 | 616433 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Additional Resources | Length |
|---|---|---|
| UniProtKB:A0A8M1RM83 | InterPro | 678 |
| UniProtKB:A0AC58H981 | InterPro | 1827 |
| UniProtKB:A0AC58H993 | InterPro | 1747 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance