Gene

padi2

ID
ZDB-GENE-031116-67
Name
peptidyl arginine deiminase, type II
Symbol
padi2 Nomenclature History
Previous Names
  • sb:cb968
  • zgc:66317
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have protein-arginine deiminase activity. Involved in vasculature development. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in infertility and rheumatoid arthritis. Is expressed in epidermis; pectoral fin musculature; periderm; pharynx; and sensory system. Orthologous to several human genes including PADI2 (peptidyl arginine deiminase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
19 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With padi2 Human Ortholog
No data available
Associated With padi2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR013530 Protein-arginine deiminase, C-terminal
Domain IPR013732 Protein-arginine deiminase (PAD), N-terminal
Domain IPR013733 Protein-arginine deiminase (PAD), central domain
Family IPR004303 Protein-arginine deiminase
Homologous_superfamily IPR008972 Cupredoxin
Homologous_superfamily IPR036556 Protein-arginine deiminase, central domain superfamily
Homologous_superfamily IPR038685 PAD, N-terminal domain superfamily
Domain Details Per Protein
Protein Length Cupredoxin PAD, N-terminal domain superfamily Protein-arginine deiminase Protein-arginine deiminase, central domain superfamily Protein-arginine deiminase, C-terminal Protein-arginine deiminase (PAD), central domain Protein-arginine deiminase (PAD), N-terminal
UniProtKB:A0A8M2BJY4 675
UniProtKB:Q6PFK7 647
UniProtKB:A0A8M2BJD0 701
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-padi2 polyclonal Rabbit
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations