Gene

cflara

ID
ZDB-GENE-030826-3
Name
CASP8 and FADD-like apoptosis regulator a
Symbol
cflara Nomenclature History
Previous Names
  • cflar
  • Clarp1 (1)
  • FLIP (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have cysteine-type endopeptidase activity involved in apoptotic signaling pathway. Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process and apoptotic process. Predicted to localize to cytoplasm. Orthologous to human CFLAR (CASP8 and FADD like apoptosis regulator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Sakamaki et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cflara Human Ortholog
No data available
Associated With cflara Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001309 Peptidase C14, p20 domain
Domain IPR001875 Death effector domain
Domain IPR015917 Peptidase C14A, caspase catalytic domain
Homologous_superfamily IPR011029 Death-like domain superfamily
Homologous_superfamily IPR029030 Caspase-like domain superfamily
Domain Details Per Protein
Protein Length Caspase-like domain superfamily Death effector domain Death-like domain superfamily Peptidase C14A, caspase catalytic domain Peptidase C14, p20 domain
UniProtKB:A0A8M1P2J9 461
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cflar monoclonal Rabbit
  • WB
Cell Signaling Technology, Inc.
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations