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General Information
ZIRC
ZFIN ID: ZDB-GENE-030826-3
Gene Name: CASP8 and FADD-like apoptosis regulator a
Gene Symbol: cflara
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: cflar, Clarp1 (1), FLIP (1)

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(Including Attributions)
Location: Chr: 11 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have cysteine-type endopeptidase activity involved in apoptotic process. Predicted to be involved in apoptotic process. Predicted to localize to the cytoplasm. Orthologous to human CFLAR  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2599 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa11641 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27804 Point Mutation Unknown Splice Site ENU
    sa27805 Point Mutation Unknown Splice Site ENU
    sa41869 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH cflara HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cflara VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component cytoplasm (more)
    Molecular Function cysteine-type endopeptidase activity (more)
    GO Terms (all 11)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cflara-201 (1) 2273
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cflara No data available
    MARKER RELATIONSHIPS
    cflaraContained in: [BAC] DKEY-31D5 (1) (order this), DKEY-245J21 (1) (order this)
    cflaraEncodes: [cDNA] MGC:136515 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001313772 (1)
    Genomic GenBank:BX323548 (1) 222367bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R706 (1) 461aa
    Sequence Clusters UniGene:159804 (1)
    Sequence Information (all 22)
    ORTHOLOGY for cflara (Chr: 11)
    CITATIONS (27)