Gene

si:ch211-204c21.1

ID
ZDB-GENE-030429-35
Name
si:ch211-204c21.1
Symbol
si:ch211-204c21.1 Nomenclature History
Previous Names
  • sb:cb458
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have DNA binding activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway; positive regulation of endocytosis; and receptor-mediated endocytosis. Predicted to localize to cytoplasm and plasma membrane. Is expressed in several structures, including alar plate midbrain region; brain; hypochord; mesoderm; and pectoral fin. Orthologous to human DAB2 (DAB adaptor protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With si:ch211-204c21.1 Human Ortholog
No data available
Associated With si:ch211-204c21.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR048559 Disabled homolog 1/2, sulfatide-binding motif
Domain IPR006020 PTB/PI domain
Domain IPR048561 Disabled, phosphotyrosine-binding domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Disabled homolog 1/2, sulfatide-binding motif Disabled, phosphotyrosine-binding domain PH-like domain superfamily PTB/PI domain
UniProtKB:A0A8M9P909 668
UniProtKB:A0A8M9QEV1 229
UniProtKB:A0A8M9Q4D7 419
UniProtKB:A0A8M9PZ11 454
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:ch211-204c21.1-201 (1) Ensembl 1,885 nt
mRNA si:ch211-204c21.1-202 (1) Ensembl 1,230 nt
mRNA si:ch211-204c21.1-203 (1) Ensembl 6,805 nt
mRNA si:ch211-204c21.1-204 (1) Ensembl 6,317 nt
mRNA si:ch211-204c21.1-205 (1) Ensembl 6,718 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations