Gene
pepd
- ID
- ZDB-GENE-030131-9444
- Name
- peptidase D
- Symbol
- pepd Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have aminopeptidase activity and manganese ion binding activity. Involved in endocrine pancreas development and pancreas regeneration. Human ortholog(s) of this gene implicated in prolidase deficiency. Is expressed in blood vessel; eye; neural crest; optic vesicle; and yolk syncytial layer. Orthologous to human PEPD (peptidase D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1000 (9 images)
- eu591 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from O'Hare et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| prolidase deficiency | Alliance | Prolidase deficiency | 170100 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001131 | Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site |
| Domain | IPR000994 | Peptidase M24 |
| Domain | IPR007865 | Aminopeptidase P, N-terminal |
| Homologous_superfamily | IPR029149 | Creatinase/Aminopeptidase P/Spt16, N-terminal |
| Homologous_superfamily | IPR036005 | Creatinase/aminopeptidase-like |
Domain Details Per Protein
| Protein | Length | Aminopeptidase P, N-terminal | Creatinase/aminopeptidase-like | Creatinase/Aminopeptidase P/Spt16, N-terminal | Peptidase M24 | Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A0G2KZA4
|
498 | |||||
|
UniProtKB:Q7SXT5
|
496 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available